Aluminum Hydroxide Overview

Aluminum Hydroxide is an inorganic salt used as an antacid that cures/reduces acidity in the gastrointestinal tract, including the oral cavity, pharynx, esophagus, stomach, small intestine, large intestine, and anal canal.

Key Properties of Aluminum Hydroxide

Product Name: Aluminum hydroxide
Synonyms: Aluminium trihydroxide, Aluminium trihydrate, Aluminium hydrate
CAS No: 21645-51-2
Chemical Formula: Al(OH)₃
Grade: IP/BP/USP
Appearance: White or almost white fine powder
Molar Mass: 78.00 g/mol
Solubility: Soluble in dil. Mineral acid and sol. of fixed alkali hydroxide. Insoluble in water and alcohol.

Manufacturing process of Aluminum Hydroxide

The process starts with checking equipment cleanliness and verifying the availability of utilities, raw materials, and packing materials.

Charge Purified water is into a reactor and add aluminum salts, such as aluminum chloride or aluminum sulfate, are added under continuous stirring. The pH of the solution is adjusted with an alkali, like sodium hydroxide, to precipitate aluminum hydroxide. The reaction is maintained at 50–60°C with continuous stirring until complete precipitation occurs.

The aluminum hydroxide precipitate is separated using a centrifugation operation and wash wet cake with with purified water to remove impurities.

The wet aluminum hydroxide is then dried at 80–120°C until the desired moisture content is achieved. The dried material is milled for uniform particle size and sieved through a specified mesh size. After quality control checks, Pack Aluminum Hydroxide in a clear poly bag and twist the mouth of the bag. Secure it with a PVC strip. Place this bag inside another poly bag, twist its mouth, and secure it with a PVC strip. Finally, place the sealed bag in an HDPE container. Store Aluminum Hydroxide in a tightly closed, light-resistant container at a temperature below 30°C.

Applications of Aluminum Hydroxide

Therapeutic Uses
Antacid for Acid Reflux and Indigestion
Aluminum hydroxide neutralizes stomach acid, providing relief from heartburn and indigestion.
Phosphate Binder in Renal Disease
It helps control phosphate levels in kidney disease patients by preventing phosphate absorption.
Treatment of Peptic Ulcers
It reduces stomach acidity, protecting the stomach lining and aiding in ulcer healing.

Industrial Uses
Pharmaceutical Formulations
Aluminum hydroxide is used in antacid tablets, suspensions, and capsules for gastrointestinal relief.
R&D and Formulation Development
It’s researched for creating new drug delivery systems, like chewable tablets and combination therapies, to improve treatment outcomes and patient compliance.

Technical Specifications of Aluminum Hydroxide

Sr.No. Test Specification
01 Appearance White or almost white fine powder
02 Solubility Soluble in dil. Mineral acid and sol. of fixed alkali hydroxide. Insoluble in water and alcohol
03 Identification (Test A&B) A) By IR Spectrophotometer
B) It gives reaction of aluminium
04 Assay as Al(OH)3 Not less than 76.5% of Al(OH)3
05 Acid Neutralizing Capacity Not less than 25 mEq per gm
06 Chloride Not more than 0.85%
07 Sulphates Not more than 0.60%
08 Arsenic Not more than 8 ppm
09 Heavy Metals Not more than 0.006%
10 pH Not more than 10
11 Microbial contamination Bile tolerant gram negative bacteria absent per gm
Escherichia coli absent per gm
TAMC Not more than 1000 cfu/gm
TYMC Not more than 100 cfu/gm
12 Loss on Drying Not more than 2.0%
13 Particle size 95% Minimum passes through 300 Mesh

 

Note: Additional test to be carried out as per customer requirements.

Packing and Storage condition of Aluminum Hydroxide

Pack Aluminum Hydroxide in a clear poly bag and twist the mouth of the bag. Secure it with a PVC strip. Place this bag inside another poly bag, twist its mouth, and secure it with a PVC strip. Finally, place the sealed bag in an HDPE container. Store Aluminum Hydroxide in a tightly closed, light-resistant container at a temperature below 30°C.

MSDS - Aluminum Hydroxide

Download MSDS

Why Choose Chemignition for
Aluminum Hydroxide Supply?

Quality Assurance

Grade Compliance

Aluminum Hydroxide is manufactured in adherence to stringent global pharmaceutical standards.

In-House Quality Control

Each batch undergoes rigorous testing for purity, stability, and efficacy.

Regulatory Approvals

Certified for export and compliant with international regulatory requirements.

Large-Scale Manufacturing and Export

Grade Compliance

Aluminum Hydroxide is manufactured in adherence to stringent global pharmaceutical standards.

In-House Quality Control

Each batch undergoes rigorous testing for purity, stability, and efficacy.

Regulatory Approvals

Certified for export and compliant with international regulatory requirements.

How to Order Aluminum Hydroxide

For bulk orders or more information about Adapalene, contact our sales team today:
 
Email
info@chemignition.com
Phone
+91 8866558673

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    FAQs related to Aluminum Hydroxide API

    What is the purity level of Chemignition’s Aluminum Hydroxide?

    Our Aluminum Hydroxide API can be more then 99% pure and meets industry standards with high purity levels to ensure efficacy in antacid products.

    How is Aluminum Hydroxide packaged and stored for optimal stability?

    Pack Aluminum Hydroxide in a clear poly bag and twist the mouth of the bag. Secure it with a PVC strip. Place this bag inside another poly bag, twist its mouth, and secure it with a PVC strip. Finally, place the sealed bag in an HDPE container. Store Aluminum Hydroxide in a tightly closed, light-resistant container at a temperature below 30°C.

    What regulatory certifications does your Aluminum Hydroxide comply with?

    Our Aluminum Hydroxide complies with major international regulatory standards, including FDA, GMP, and ISO 9001.

    Can you provide batch-specific documentation and COAs (Certificates of Analysis)?

    Yes, we provide complete documentation and COAs for each batch to ensure transparency and quality.

    How do you ensure consistent supply and timely delivery of Aluminum Hydroxide?

    We have a reliable supply chain and efficient production processes to meet your timelines and ensure consistent delivery.

    What is the shelf life of your Aluminum Hydroxide API?

    Our Aluminum Hydroxide has a shelf life of up to 72 months when stored under recommended conditions.

    Do you offer custom formulations or concentrations of Aluminum Hydroxide?

    Yes, we can customize formulations to meet your specific product requirements.

    What therapeutic usage of Aluminum Hydroxide?

    Aluminum Hydroxide is used as an antacid to cure/reduce acidity in the gastrointestinal tract, including the oral cavity, pharynx, esophagus, stomach, small intestine, large intestine, and anal canal.

    What is usage of Aluminum Hydroxide API?

    Aluminum Hydroxide API is used for manufacturing the following formulations: 300 mg to 600 mg tablets, 320 mg to 600 mg per 5 mL suspension, and 600 mg to 1200 mg per 10 mL gel.