Key Properties of Magnesium Citrate
| Product Name: | Magnesium Citrate Anhydrous |
| Synonyms: | Tribasic Magnesium Citrate, Magnesium Salt of Citric Acid (Anhydrous) |
| CAS No: | 7779-25-1 |
| Chemical Formula: | C₁₂H₁₀Mg₃O₁₄ |
| Grade: | BP / USP |
| Appearance: | White to off-white crystalline powder |
| Molar Mass: | 451.11 g/mol |
| Solubility: | Freely soluble in water; practically insoluble in ethanol |
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WhatsappMagnesium Citrate Manufacturing process
Magnesium Citrate is manufactured through a carefully controlled process to ensure high purity, consistent quality, and compliance with pharmaceutical, nutraceutical, and food-grade standards.
Step 1: Raw Material Selection
High-quality citric acid and a suitable magnesium source are selected and tested to ensure they meet the required quality specifications.
Step 2: Preparation of Solutions
Citric acid is dissolved in purified water to prepare a clear solution. The magnesium source is separately prepared in the required concentration.
Step 3: Controlled Reaction
The magnesium solution is gradually added to the citric acid solution under continuous stirring. The reaction is carried out under controlled temperature and pH conditions to ensure complete formation of Magnesium Citrate.
Step 4: pH Adjustment
The reaction mixture is monitored continuously, and the pH is adjusted as required to achieve complete conversion and obtain the desired product quality.
Step 5: Maturation
The reaction mixture is allowed to mature under controlled conditions to ensure complete reaction and uniform crystal formation.
Step 6: Crystallization
The solution is cooled under controlled conditions, allowing Magnesium Citrate crystals to form. Process parameters are carefully maintained to achieve the desired crystal size and purity.
Step 7: Filtration
The crystallized Magnesium Citrate is separated from the mother liquor using suitable filtration equipment to remove the liquid phase and process impurities.
Step 8: Washing
The filtered crystals are washed with purified water to remove residual soluble impurities and improve product purity.
Step 9: Drying
The washed Magnesium Citrate is dried under controlled temperature and humidity conditions using suitable drying equipment until the required moisture content is achieved. The dried product is then ready for milling, quality testing, and packaging.
Magnesium Citrate Applications
Pharmaceutical Applications
Osmotic Laxative Formulations
Bowel Preparation Formulations
Magnesium Source in Pharmaceutical Formulations
Nutraceutical Applications
Magnesium Supplement Formulations
Mineral and Multimineral Supplements
Powder and Drink-Mix Formulations
Food and Beverage Applications
Magnesium Fortification
Nutritional Formulations
Chemical and Formulation Applications
Magnesium and Citrate Source
Specialty Formulation Applications
Laboratory and Research Applications
Laboratory Reagent and Research Use
Magnesium Citrate Specifications
Magnesium Citrate USP Specification
Download Magnesium Citrate USP Specification
| Sr. No. | Test | Specification |
|---|---|---|
| 1 | Description | White or almost white, fine, slightly hygroscopic powder. |
| 2 | Solubility | Soluble in water, practically insoluble in ethanol (96 per cent). It dissolves in dilute hydrochloric acid. |
| 3 | Identification by Magnesium | It gives reaction of Magnesium. |
| 4 | Identification by Citrate | It gives reaction of Citrate. |
| 5 | Chloride | Not more than 0.05% |
| 6 | Sulphate | Not more than 0.20% |
| 7 | Arsenic | Not more than 3 ppm |
| 8 | Iron | Not more than 200 ppm |
| 9 | Calcium | Not more than 1.0% on the dried basis |
| 10 | pH | 5.0 to 9.0 |
| 11 | Loss on Drying | Not more than 2.0% |
| 12 | Assay – Magnesium (on dried basis) | Not less than 14.50% and not more than 16.40% Mg |
Magnesium Citrate BP Specification
Download Magnesium Citrate BP Specification
| Sr. No. | Test | Specification |
|---|---|---|
| 1 | Description | White or almost white, fine, slightly hygroscopic powder. |
| 2 | Solubility | Soluble in water, practically insoluble in ethanol (96 per cent). It dissolves in dilute hydrochloric acid. |
| 3 | Identification by Magnesium | It gives reaction of Magnesium. |
| 4 | Identification by Citrate | It gives reaction of Citrate. |
| 5 | Appearance of Solution | Not more intensely coloured than reference solution. |
| 6 | pH | 6.0 to 8.5 |
| 7 | Oxalates | Not more than 280 ppm |
| 8 | Sulfates | Not more than 0.2% |
| 9 | Calcium | Not more than 0.2% |
| 10 | Iron | Not more than 100 ppm |
| 11 | Loss on Drying | Not more than 3.5% |
| 12 | Assay – Magnesium (dried substance) | 15.00% to 16.50% of Mg |
Magnesium Citrate Packing and Storage condition
Packing:
Packed in 25 kg / 50 kg HDPE bags with inner liner.
Available in fiber drums or customized packaging as per customer requirements.
Tamper-proof and moisture-resistant packaging ensures product stability.
Storage:
Store in a cool, dry, and well-ventilated area away from moisture.
Keep the container tightly closed to prevent contamination.
Avoid exposure to direct sunlight and incompatible materials (such as strong acids).
Recommended storage temperature: Below 30°C.
Magnesium Citrate MSDS/SDS
Why Choose Chemignition for
Magnesium Citrate Supply?
Quality Assurance
Grade Compliance
Magnesium Citrate is manufactured in adherence to stringent global pharmaceutical standards.
In-House Quality Control
Each batch undergoes rigorous testing for purity, stability, and efficacy.
Regulatory Approvals
Certified for export and compliant with international regulatory requirements.
Large-Scale Manufacturing and Export
Grade Compliance
Magnesium Citrate is manufactured in adherence to stringent global pharmaceutical standards.
In-House Quality Control
Each batch undergoes rigorous testing for purity, stability, and efficacy.
Regulatory Approvals
Certified for export and compliant with international regulatory requirements.
