Calcium Citrate Overview

Calcium Citrate is a highly bioavailable calcium salt widely used as an active ingredient in pharmaceutical, nutraceutical, and food formulations to support bone health and calcium supplementation. Known for its excellent solubility and superior absorption, even in individuals with low stomach acid, Calcium Citrate plays a vital role in maintaining healthy bones, teeth, muscle function, and nerve transmission. It is scientifically recognized for effectively helping prevent and treat calcium deficiency while supporting overall skeletal health with excellent gastrointestinal tolerability.

Key Properties of Calcium Citrate

Product Name: Calcium Citrate
Synonyms: Calcium Salt of Citric Acid
CAS No: 5785-44-4
Chemical Formula: C₁₂H₁₀Ca₃O₁₄·4H₂O
Grade: IP / BP / USP
Appearance: White, fine crystalline powder or granular powder
Molar Mass: 570.50 g/mol
Solubility: Slightly soluble in water; practically insoluble in ethanol (96%)

Manufacturing process of Calcium Citrate

Calcium Citrate is manufactured through a carefully controlled neutralization and crystallization process to ensure high purity, consistent quality, and compliance with pharmaceutical and food-grade standards.

Step 1: Raw Material Selection

High-quality calcium sources and purified citric acid are selected and tested to ensure compliance with predefined quality specifications.

Step 2: Neutralization Reaction

Citric acid is gradually reacted with the calcium source under controlled temperature, pH, and agitation conditions to form Calcium Citrate.

Step 3: Purification

The reaction mixture is purified to remove any unreacted materials and process-related impurities, ensuring the desired product quality.

Step 4: Filtration

The purified slurry is filtered to separate the Calcium Citrate crystals from the liquid phase.

Step 5: Washing

The filtered crystals are thoroughly washed with purified water to remove residual impurities and soluble salts.

Step 6: Drying

The washed Calcium Citrate is dried under controlled temperature conditions to achieve the required moisture content without affecting product quality.

Applications of Calcium Citrate

Pharmaceutical Industry
Drug Formulation
Used as a calcium supplement in tablets, capsules, and oral powders. Helps prevent and treat calcium deficiency. Used in formulations for bone health and osteoporosis management. Included in multivitamin and mineral preparations.

Nutraceutical Industry
Formulation
Widely used in dietary supplements for calcium supplementation. Supports bone, teeth, and muscle health. Used in sports nutrition and wellness products. Included in formulations for healthy aging and overall mineral supplementation.

Food Industry
Food and beverages
Used as a calcium fortification ingredient in food and beverages. Added to dairy products, cereals, fruit juices, and nutritional foods. Used in functional foods and health drinks. Serves as a reliable source of dietary calcium.

Chemical Industry
Chemical
Used as a raw material in specialty chemical formulations. Utilized in laboratory and research applications.

Technical Specifications of Calcium Citrate

Sr. No. Test Specification
1 Description White, fine crystalline powder
2 Identification Complies with the test for Calcium and Citrate
3 Assay 97.5% – 100.5% (on dried basis)
4 Loss on Drying Not more than 10.0%
5 pH (Suspension) 5.5 – 8.0
6 Solubility Slightly soluble in water; practically insoluble in ethanol
7 Chloride (Cl⁻) Not more than 500 ppm
8 Sulphate (SO₄²⁻) Not more than 1000 ppm
9 Iron (Fe) Not more than 50 ppm
10 Heavy Metals Not more than 20 ppm
11 Lead (Pb) Not more than 2 ppm
12 Arsenic (As) Not more than 3 ppm
13 Residue on Ignition Not more than 0.2%
Note: Additional test to be carried out as per customer requirements.

Packing and Storage condition of Calcium Citrate

Packing:
Packed in 25 kg / 50 kg HDPE bags with inner liner.
Available in fiber drums or customized packaging as per customer requirements.
Tamper-proof and moisture-resistant packaging ensures product stability.

Storage:
Store in a cool, dry, and well-ventilated area away from moisture.
Keep the container tightly closed to prevent contamination.
Avoid exposure to direct sunlight and incompatible materials (such as strong acids).
Recommended storage temperature: Below 30°C.

MSDS - Calcium Citrate

Why Choose Chemignition for
Calcium Citrate Supply?

Quality Assurance

Grade Compliance

Calcium Citrate is manufactured in adherence to stringent global pharmaceutical standards.

In-House Quality Control

Each batch undergoes rigorous testing for purity, stability, and efficacy.

Regulatory Approvals

Certified for export and compliant with international regulatory requirements.

Large-Scale Manufacturing and Export

Grade Compliance

Calcium Citrate is manufactured in adherence to stringent global pharmaceutical standards.

In-House Quality Control

Each batch undergoes rigorous testing for purity, stability, and efficacy.

Regulatory Approvals

Certified for export and compliant with international regulatory requirements.

How to Order Calcium Citrate

For bulk orders or more information about Adapalene, contact our sales team today:
 
Email
info@chemignition.com
Phone
+91 8866558673

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    FAQs related to Calcium Citrate API

    What is Calcium Citrate?

    Calcium Citrate is a calcium salt of citric acid widely used in pharmaceutical, nutraceutical, food, and dietary supplement formulations. It is valued for its high bioavailability and excellent absorption.

    Which grades of Calcium Citrate are available?

    Calcium Citrate is available in pharmaceutical, food, and nutraceutical grades, depending on the intended application and regulatory requirements.

    Does Chemignition provide regulatory documentation?

    Yes. Chemignition provides essential documentation such as COA, MSDS/SDS, TDS, and other quality documents as required by customers.

    Does Chemignition export Calcium Citrate internationally?

    Yes. Chemignition supplies high-quality Calcium Citrate to domestic and international customers while ensuring compliance with applicable quality and regulatory standards.

    Can Chemignition provide bulk quantities of Calcium Citrate?

    Yes. Chemignition offers Calcium Citrate in bulk quantities for pharmaceutical, nutraceutical, food, and industrial applications with reliable global supply.

    How can I request a quotation for Calcium Citrate?

    You can contact Chemignition’s sales team with your required grade, quantity, and destination. Our team will provide a competitive quotation along with the required technical documentation.