Potassium citrate Overview

Chemignition Laboratory, a GMP and ISO 9001-certified manufacturer, ensures the highest quality standards in producing Potassium Citrate. Our Potassium Citrate IP/BP/USP/FCC meets stringent pharmaceutical and food-grade specifications. It is widely used as a buffering agent, acidity regulator, and dietary supplement. We prioritize purity, safety, and compliance in every batch we manufacture. Chemignition Laboratory is committed to delivering premium-quality Potassium Citrate to global industries.

Key Properties of Potassium citrate

Product Name: Potassium Citrate
Synonyms: Tripotassium citrate
CAS No: 6100-05-6
Chemical Formula: C₆H₅K₃O₇
Grade: IP / BP / USP / FCC
Appearance: White crystalline powder or granules
Molar Mass: 306.39 g/mol
Solubility: Freely soluble in water, insoluble in alcohol
Melting Point: Decomposes before melting

Manufacturing process of Potassium citrate

1. Raw Material Selection:

  • Procure high-purity Citric Acid and Potassium Hydroxide / Potassium Carbonate as primary raw materials.
  • Ensure all raw materials meet pharmaceutical (IP/BP/USP) or food-grade (FCC) quality standards.

2. Solution Preparation:

  • Dissolve Citric Acid in purified water to prepare a citric acid solution.
  • Separately, dissolve Potassium Hydroxide or Potassium Carbonate in purified water.

3. Reaction and Mixing:

  • Gradually add the potassium solution to the citric acid solution under controlled conditions.
  • Maintain stirring and temperature control to ensure complete reaction.
  • Continuously monitor pH and concentration to achieve the desired Potassium Citrate solution.

4. Filtration:

  • The reaction mixture is filtered to remove any undissolved impurities or solid particles.
  • Use multi-stage filtration for high-purity product.

5. Concentration (Evaporation Process):

  • The filtered solution is concentrated using evaporators to remove excess water.
  • Control temperature and vacuum settings to prevent product degradation.

6. Crystallization:

  • The concentrated solution is cooled gradually to induce crystallization of Potassium Citrate.
  • Control cooling rate and agitation for uniform crystal formation.

7. Centrifugation & Drying:

  • Crystals are separated using centrifugation or filtration.
  • The wet product is dried in fluid bed dryers (FBD) or vacuum dryers to achieve the desired moisture content.

8. Milling & Sieving:

  • The dried Potassium Citrate is milled and passed through a vibro sifter to obtain the required particle size distribution (PSD).

9. Quality Control & Testing:

  • The final product undergoes rigorous quality control (QC) tests, including:
    • Purity & Assay (IP/BP/USP/FCC standards)
    • Moisture content
    • pH and solubility
    • Heavy metals & microbial limits

10. Packaging & Storage:

  • The finished Potassium Citrate is packed in double-layer polybags inside HDPE drums or fiber drums.
  • Labeled as per regulatory requirements and stored in a cool, dry place to maintain stability.

Applications of Potassium citrate

Pharmaceutical Industry
Urinary Alkalizer
Used to prevent kidney stones and manage urinary tract infections by alkalizing urine.
Electrolyte Replacement
Helps maintain electrolyte balance in patients with low potassium levels.
Pharmaceutical Excipient
Used as a buffering agent in various drug formulations.

Food Industry
Food Additive
Acts as a food additive for acidity regulation and preservation.
Potassium Supplement
Used as a dietary supplement to provide essential potassium.
pH Regulator
Helps in maintaining the pH balance in food and beverages.

Chemical Industry
Buffering Agent
Used in industrial applications as a buffering agent to maintain stability.
Water Treatment
Used in water softening and purification processes.
Detergent Industry
Functions as a water softener in detergent formulations to improve cleaning efficiency.

Technical Specifications of Potassium citrate

Sr. No. Test Specification
1 Description White crystalline powder or granules
2 Assay (Purity) 99.0% – 100.5%
3 Loss on Drying 3.0% – 6.0%
4 pH (5% solution) 7.5 – 9.0
5 Solubility Freely soluble in water, insoluble in alcohol
6 Chloride (Cl⁻) Not more than 50 ppm
7 Sulphate (SO₄²⁻) Not more than 150 ppm
8 Heavy Metals Not more than 10 ppm
9 Iron (Fe) Not more than 5 ppm
10 Lead (Pb) Not more than 2 ppm
11 Arsenic (As) Not more than 1 ppm
12 Residue on Ignition Not more than 0.1%
Note: Additional test to be carried out as per customer requirements.

Packing and Storage condition of Potassium citrate

Packing:

  • Potassium Citrate is packed in HDPE drums, fiber drums, or kraft paper bags with inner double-layer polyethylene liners to ensure product stability.
  • Standard packaging sizes include 25 kg or 50 kg bags/drums.
  • Custom packaging options are available based on specific requirements.

Storage Conditions:

  • Store in a cool, dry, and well-ventilated area away from moisture, heat, and direct sunlight.
  • Keep the container tightly closed to prevent contamination and maintain product integrity.
  • Recommended storage temperature: Below 30°C.

MSDS - Potassium citrate

Why Choose Chemignition for
Potassium citrate Supply?

Quality Assurance

Grade Compliance

Potassium citrate is manufactured in adherence to stringent global pharmaceutical standards.

In-House Quality Control

Each batch undergoes rigorous testing for purity, stability, and efficacy.

Regulatory Approvals

Certified for export and compliant with international regulatory requirements.

Large-Scale Manufacturing and Export

Grade Compliance

Potassium citrate is manufactured in adherence to stringent global pharmaceutical standards.

In-House Quality Control

Each batch undergoes rigorous testing for purity, stability, and efficacy.

Regulatory Approvals

Certified for export and compliant with international regulatory requirements.

How to Order Potassium citrate

For bulk orders or more information about Adapalene, contact our sales team today:
 
Email
info@chemignition.com
Phone
+91 8866558673

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    FAQs related to Potassium citrate API

    What is Potassium Citrate?

    Potassium Citrate is a potassium salt of citric acid, commonly used in pharmaceuticals, food, and industrial applications. It helps regulate acidity and serves as a potassium supplement.

    What are the uses of Potassium Citrate?
    • As a urinary alkalizer in pharmaceuticals to prevent kidney stones.
    • As a food additive to regulate acidity and improve flavor.
    • In industrial applications, such as buffer solutions and water treatment.
    What are the benefits of Potassium Citrate in pharmaceuticals?

    Potassium Citrate helps prevent kidney stones by increasing urine pH and reducing the formation of calcium oxalate and uric acid stones. It is also used to treat conditions like metabolic acidosis.

    What is the chemical formula of Potassium Citrate?

    The chemical formula is K₃C₆H₅O₇.

    What are the different grades of Potassium Citrate available?

    Potassium Citrate is available in IP, BP, USP, and Food Grade standards, ensuring suitability for pharmaceutical and food applications.

    How is Potassium Citrate stored?

    It should be stored in a cool, dry place, away from moisture and direct sunlight, in tightly closed containers to maintain stability and purity.

    Is Chemignition Laboratory a manufacturer of Potassium Citrate?

    Yes, Chemignition Laboratory is a leading manufacturer and exporter of Potassium Citrate with GMP and ISO 9001 certification. Our high-quality manufacturing processes ensure compliance with industry standards for pharmaceutical, food, and industrial applications.

    Why choose Chemignition Laboratory for Potassium Citrate?
    • GMP and ISO 9001 certified manufacturing facility.
    • High-purity IP/BP/USP/Food Grade Potassium Citrate.
    • Strict Quality Management Systems (QMS) compliance.
    • Global supplier with a strong reputation for excellence.