| Product Name: | Lubiprostone |
| Synonyms: | 7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-yl]heptanoic acid |
| CAS No: | 333963-40-9 |
| Chemical Formula: | C20H32F2O5 |
| Grade: | USP/IP/IH |
| Appearance: | White to off-white crystalline powder |
| Molar Mass: | 390.56 g/mol |
| Solubility: | Insoluble in water but is soluble in organic solvents |
Description
Chemignition is a leading manufacturer and exporter of Lubiprostone Active Pharmaceutical Ingredients (API) worldwide. The company adheres to strict Quality Management Systems (QMS) to ensure compliance with Good Manufacturing Practices (cGMPs). This commitment to quality and regulatory standards guarantees that Chemignition produces Lubiprostone of the highest quality and efficacy.
Healthcare providers use Lubiprostone to treat bowel obstruction in the small or large intestine. This medication increases fluid flow in the intestine, softens the stool, and facilitates easier passage. Additionally, Lubiprostone enhances intestinal motility.
During the manufacturing of Active Pharmaceutical Ingredients (API) and specialty chemicals, Chemignition performs various processes, including dissolution, charcoalization, filtration, leaching, extraction, crystallization, and purification.
Manufacturers commonly use Lubiprostone API to produce pharmaceutical products such as capsules and liquid-filled forms.
The U.S. Food and Drug Administration (FDA) approved Lubiprostone in 2006 for the treatment of chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). This approval marked a significant advancement in managing these gastrointestinal conditions, demonstrating its safety and efficacy in clinical use.
Storage Conditions: Pack Lubiprostone in tightly closed vials and maintain it in a sealed container, stored at a temperature between -20°C and -10°C.