Zinc Oxide (ZnO) is a white, odorless powder widely used in the pharmaceutical industry for its anti-inflammatory, antibacterial, and healing properties. Whether in a baby rash cream or an antiseptic paste, this mineral-based compound plays a vital role in a range of medicinal formulations.
In this blog, we’ll explore what Zinc Oxide is used for in pharma, its benefits, applications, and why pharma-grade ZnO must meet IP/BP/USP standards to ensure safety, efficacy, and compliance.
What is Zinc Oxide?
Zinc Oxide is an inorganic compound (chemical formula: ZnO) that’s insoluble in water and widely known for its non-toxic, skin-safe properties. It is manufactured via two primary methods:
- French Process (Indirect): High-purity ZnO for pharma & cosmetics
- American Process (Direct): Lower-grade ZnO for industrial use
Only GMP-certified Zinc Oxide manufactured under clean, controlled conditions is acceptable for regulated pharmaceutical applications.
Pharmaceutical Applications of Zinc Oxide
1. Topical Creams & Ointments
Zinc Oxide is best known for its use in:
- Diaper rash creams
- Antiseptic ointments
- Anti-acne creams
- Eczema and dermatitis treatments
- Burn and wound healing ointments
Its astringent and barrier-forming properties protect the skin from irritation, promote healing, and prevent microbial infections.
2. Oral Formulations
Zinc is an essential trace mineral, and in some regions, Zinc Oxide is used in oral pharmaceutical preparations:
- Dietary supplements for zinc deficiency
- Immune system support formulations
- Zinc-fortified syrups and tablets (in controlled dosage)
3. Dental Products
Zinc Oxide is also used in:
- Temporary dental cements
- Toothpaste formulations
- Antibacterial mouth pastes
When mixed with eugenol, ZnO forms a paste with excellent sealing and antibacterial properties used in dental procedures.
4. Wound Dressings & Powders
Pharma-grade ZnO is incorporated into:
- Medicated bandages and dressings
- Anti-fungal powders
- Post-surgical healing products
It helps reduce irritation, absorb moisture, and acts as a mild antiseptic.
Regulatory Grades for Pharmaceutical Use
To be used safely in pharmaceuticals, Zinc Oxide must comply with:
- IP (Indian Pharmacopoeia)
- BP (British Pharmacopoeia)
- USP (United States Pharmacopeia)
These standards regulate:
- Purity (typically ≥99%)
- Heavy metal limits (Lead, Arsenic, Mercury)
- Particle size
- Loss on drying
- pH level and solubility
Key Benefits of Zinc Oxide in Pharma
| Benefit | Pharmaceutical Impact |
|---|---|
| Anti-inflammatory | Reduces redness and irritation in creams |
| Antimicrobial | Helps prevent infections in wounds or rashes |
| Astringent | Tightens skin and shrinks tissue |
| Moisture Barrier | Protects skin from external irritants |
| Healing Support | Accelerates recovery of minor cuts and abrasions |
Global Compliance & Safety
For international supply, Zinc Oxide used in pharmaceuticals must come with:
- GMP Certificate
- COA (Certificate of Analysis)
- MSDS (Material Safety Data Sheet)
- Non-GMO and Allergen-Free Declarations
- ISO 9001:2015 Certification
Suppliers like Chemignition Laboratory provide all regulatory support and export-ready documentation for pharma clients worldwide.
Why Choose Chemignition’s Pharma-Grade Zinc Oxide?
Chemignition Laboratory is a GMP-certified Zinc Oxide manufacturer and exporter, delivering IP/BP/USP grade ZnO to pharmaceutical firms globally.
| Features | Details |
|---|---|
| High Purity ZnO (≥99%) | Safe for topical and oral formulations |
| Regulatory Grade (IP/BP/USP) | Acceptable in regulated markets |
| Batch COA, MSDS, and TDS Provided | Full traceability and compliance |
| Custom Mesh Sizes | Micronized or standard for creams & powders |
| Export Documentation Support | Customs-ready, including certificates of origin |
Packaging Options
| Pack Type | Weight Options | Usage |
|---|---|---|
| HDPE Drums | 25 kg / 50 kg | Bulk pharma and topical use |
| Polybags | 1–5 kg | R&D and formulation labs |
| OEM Labeling | Custom | White-label pharma brands |
Get in Touch
Need a reliable pharma-grade Zinc Oxide supplier?
- Request a sample
- Share your documentation needs
- Ask for pricing and lead time
🌐 Website: www.chemignition.com
FAQs
Can Zinc Oxide be ingested?
Only pharmaceutical-grade ZnO in carefully regulated doses is used in oral supplements. Always consult regulatory guidelines.
Is your ZnO compliant with IP/BP/USP?
Yes. Chemignition offers all three grades with full documentation.
What is the minimum order quantity?
MOQ is usually 25 kg, though smaller batches for testing are available.
What is the shelf life of Zinc Oxide?
Typically 36 months, stored in a sealed container in a cool, dry place.
Do you support international documentation?
Yes. We offer COA, GMP, ISO certificates, MSDS, and origin documentation.
